Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.44 |
| ▸ | ITGAV | P06756 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168844 | 0.87 | ITGAV (0.45) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8321280 | 0.86 | ITGB3 (0.37) | ITGB3ITGAVSMN1; SMN2HTTMAPT | |
| SCHEMBL7161074 | 0.85 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL7160899 | 0.84 | PTPN1 (0.49) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7479810 | 0.82 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL7469216 | 0.82 | ITGB3 (0.39) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7161068 | 0.81 | ITGB3 (0.54) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7163734 | 0.81 | ITGB3 (0.43) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7370460 | 0.81 | ITGB3 (0.43) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7163873 | 0.81 | ITGB3 (0.47) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087057-A2 | METHODS FOR INHIBITION OF ANGIOGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-10-14 | — | — | WO | disclosed |