Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466661 | 0.93 | DRD4 (0.46) | DRD4HSD11B1HTR1AHTR7DRD3 | |
| SCHEMBL7469687 | 0.92 | DRD4 (0.44) | DRD4HTR1AHTR7DRD3HRH1 | |
| SCHEMBL7471727 | 0.90 | DRD4 (0.43) | DRD4HTR1AHTR7DRD3DRD2 | |
| SCHEMBL6168817 | 0.83 | DRD4 (0.43) | DRD4HTR1AHTR7DRD3DRD2 | |
| SCHEMBL7471893 | 0.83 | HTR1A (0.43) | HTR1AHTR7DRD3HRH1HTR2B | |
| SCHEMBL7471020 | 0.82 | DRD4 (0.49) | DRD4HTR1AHTR7DRD3DRD2 | |
| SCHEMBL7468959 | 0.82 | THRB (0.40) | DRD4THRBHTR1AHTR7DRD3 | |
| SCHEMBL6169077 | 0.82 | HTR1A (0.44) | DRD4HTR1AHTR7DRD2HTR2A | |
| SCHEMBL7466746 | 0.82 | MEN1 (0.37) | HTR1AHTR7DRD3HRH1HTR2B | |
| SCHEMBL7471009 | 0.81 | DRD4 (0.41) | DRD4HTR1ADRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755930-B1 | BENZOXAZEPINE DERIVATIVES, SALTS THEREOF, AND DRUGS CONTAINING THE SAME | SUNTORY LTD (JP) | 2002-07-31 | — | — | EP | disclosed |
| US-6337397-B1 | A BENZOXAZEPINE DERIVATIVE FOR TREATMENT OF ANXIETY NEUROSIS, PHOBIAS, OBSESSIVE-COMPULSIVE DISORDERS, SCHIZOPHRENIA, POST-CARDIAC TRAUMA STRESS DISORDERS, DEPRESSION DISORDERS, PSYCHOSOMATIC DISORDERS AND OTHER PSYCHONEUROTIC DISORDERS, | SUNTORY LIMITED (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6187769-B1 | Benzoxazepine derivatives and their salts and medicaments containing the same | SUNTORY LIMITED (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0755930-A1 | BENZOXAZEPINE DERIVATIVES, SALTS THEREOF, AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |