Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609013 | 1.00 | GGT1 (0.54) | GGT1MMEKMT2AMEN1TSHR | |
| SCHEMBL7469320 | 1.00 | GGT1 (0.54) | GGT1MMEKMT2AMEN1TSHR | |
| SCHEMBL27507226 | 0.90 | GGT1 (0.67) | GGT1KMT2ASIGMAR1CYP2D6CYP2C9 | |
| SCHEMBL4560841 | 0.90 | GGT1 (0.67) | GGT1KMT2ASIGMAR1CYP2D6CYP2C9 | |
| SCHEMBL27507225 | 0.90 | GGT1 (0.67) | GGT1KMT2ASIGMAR1CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL4561906 | 0.88 | GGT1 (0.65) | GGT1KMT2AMEN1SIGMAR1CYP2D6 | |
| SCHEMBL7466897 | 0.86 | CYP3A4 (0.45) | GGT1KMT2ATSHRSIGMAR1CA12 | |
| SCHEMBL7466905 | 0.86 | CYP3A4 (0.45) | GGT1KMT2ATSHRSIGMAR1CA12 | |
| SCHEMBL8054827 | 0.86 | CYP3A4 (0.45) | GGT1KMT2ATSHRSIGMAR1CA12 | |
| SCHEMBL27699635 | 0.86 | MME (0.56) | GGT1MMEKMT2ASIGMAR1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764648-B1 | Cephem derivatives and process for the preparation thereof | EISAI CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| EP-0333154-B1 | Process for the preparation of cephem derivatives | EISAI CO LTD (JP) | 1997-07-16 | — | — | EP | disclosed |
| EP-0764648-A1 | Cephem derivatives and process for the preparation thereof | Eisai Co., Ltd. (JP) | 1997-03-26 | — | — | EP | disclosed |
| EP-0612751-A2 | Compounds for the preparation of cephem derivatives | Eisai Co., Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5128465-A | Containing thiadiazole ring and fluorine substitution | EISAI CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0333154-A2 | Process for the preparation of cephem derivatives and intermediates therefor | Eisai Co., Ltd. (JP) | 1989-09-20 | — | — | EP | disclosed |