Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895565 | 0.73 | — | — | |
| SCHEMBL18827243 | 0.62 | — | — | |
| SCHEMBL4478843 | 0.59 | KMT2A (0.42) | HPGDTSHRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28684147 | 0.59 | HPGD (0.52) | HPGDTSHRKMT2AALDH1A1GAA | |
| SCHEMBL22684455 | 0.59 | HPGD (0.42) | HPGDTSHRRECQLKMT2AALDH1A1 | |
| SCHEMBL4475846 | 0.58 | NPC1 (0.60) | HPGDTSHRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23387941 | 0.58 | HPGD (0.55) | HPGDTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL7302106 | 0.57 | HPGD (0.50) | HPGDTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL11200191 | 0.57 | HPGD (0.50) | HPGDTSHRRECQLKMT2AALDH1A1 | |
| SCHEMBL10721733 | 0.57 | HPGD (0.95) | HPGDTSHRKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882043-B1 | HALOGEN PYRIMIDINES AND ITS USE THEREOF AS PARASITE ABATEMENT MEANS | BAYER AG (DE) | 2002-09-04 | — | — | EP | disclosed |
| US-6407233-B1 | Halogen pyrimidines and its use thereof as parasite abatement means | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | disclosed |
| US-6103717-A | STRONG FUNGICIDES; BACTERICIDES; MICROBIOCIDES; NONPHYTOTOXIC; CROPS, CEREALS, FRUITS, VEGETABLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |
| EP-0882043-A1 | HALOGEN PYRIMIDINES AND ITS USE THEREOF AS PARASITE ABATEMENT MEANS | BAYER AG (DE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997027189-A1 | HALOGEN PYRIMIDINES AND ITS USE THEREOF AS PARASITE ABATEMENT MEANS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-31 | — | — | WO | disclosed |