Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471878 | 0.89 | MAPT (0.53) | MAPTNPC1RAB9ATDP1KDM4E | |
| SCHEMBL7470170 | 0.82 | NR4A2 (0.56) | NPC1RAB9AMRGPRX4PPARDGPBAR1 | |
| SCHEMBL7471233 | 0.78 | NPC1 (0.44) | MAPTNPC1RAB9AMRGPRX4TDP1 | |
| SCHEMBL7477249 | 0.78 | MAPT (0.46) | MAPTNPC1RAB9ABCHEPPARD | |
| SCHEMBL7471939 | 0.74 | MRGPRX4 (0.41) | NPC1RAB9AMRGPRX4TDP1KDM4E | |
| SCHEMBL7471261 | 0.74 | CA12 (0.49) | MRGPRX4TPMTRXRA | |
| SCHEMBL7467175 | 0.72 | MAPT (0.44) | MAPTNPC1RAB9ATDP1KDM4E | |
| SCHEMBL5779001 | 0.72 | MAPT (0.45) | MAPTNPC1RAB9AMRGPRX4BCHE | |
| SCHEMBL23657730 | 0.71 | MAPT (1.00) | MAPTNPC1RAB9AMRGPRX4KDM4E | |
| Hydrochloric Acid SCHEMBL7473585 | 0.70 | KMT2A (0.51) | GPBAR1KMT2ANR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |