Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | VDR | P11473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27478197 | 0.88 | CYSLTR1 (0.52) | NR4A2NR4A1NR4A3CYSLTR1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL7473585 | 0.87 | KMT2A (0.51) | NR4A2NR4A1NR4A3GPBAR1CYSLTR1 | |
| SCHEMBL7469540 | 0.82 | MAPT (0.55) | NR4A2NR4A1NR4A3GPBAR1KMT2A | |
| SCHEMBL7471939 | 0.80 | MRGPRX4 (0.41) | KMT2AMRGPRX4NPC1RAB9APPARG | |
| SCHEMBL7478013 | 0.80 | PPARD (0.58) | NR4A2GPBAR1CYSLTR1MRGPRX4NPC1 | |
| SCHEMBL7477249 | 0.79 | MAPT (0.46) | KMT2ANPC1RAB9APPARD | |
| SCHEMBL7471261 | 0.79 | CA12 (0.49) | MRGPRX4 | |
| SCHEMBL7471233 | 0.79 | NPC1 (0.44) | KMT2AMRGPRX4NPC1RAB9A | |
| SCHEMBL7470860 | 0.78 | ECE1 (0.42) | KMT2AMRGPRX4NPC1RAB9A | |
| SCHEMBL7472058 | 0.78 | MEN1 (0.46) | KMT2AMRGPRX4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |