Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467175 | 0.89 | MAPT (0.44) | MAPTNPC1RAB9APPARDBCHE | |
| SCHEMBL7471233 | 0.80 | NPC1 (0.44) | MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7470170 | 0.79 | NR4A2 (0.56) | NPC1RAB9APPARDKMT2A | |
| SCHEMBL7469540 | 0.78 | MAPT (0.55) | MAPTNPC1RAB9APPARDBCHE | |
| SCHEMBL7473467 | 0.73 | NPC1 (0.45) | MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7471878 | 0.72 | MAPT (0.53) | MAPTNPC1RAB9APPARDBCHE | |
| SCHEMBL7470860 | 0.71 | ECE1 (0.42) | MAPTNPC1RAB9AHSP90AA1LMNA | |
| SCHEMBL7471939 | 0.71 | MRGPRX4 (0.41) | NPC1RAB9APPARDPPARAKMT2A | |
| SCHEMBL7471261 | 0.70 | CA12 (0.49) | — | |
| SCHEMBL15935983 | 0.70 | TAS1R3 (0.54) | EIF4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |