Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 16/20 | 0.67 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.61 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.61 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.61 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470214 | 0.90 | FKBP1A (0.58) | FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL7463760 | 0.80 | FKBP1A (0.62) | FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL7460552 | 0.78 | FKBP1A (0.63) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL16310240 | 0.77 | FKBP1A (0.89) | FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL7251704 | 0.77 | FKBP1A (0.90) | FKBP1AABCC1FKBP4FKBP5 | |
| Biricodar SCHEMBL29405867 | 0.76 | FKBP1A (1.00) | FKBP1AABCC1FKBP4FKBP5 | |
| Biricodar SCHEMBL7546702 | 0.76 | FKBP1A (1.00) | FKBP1AABCC1FKBP4FKBP5 | |
| Biricodar SCHEMBL13038499 | 0.76 | FKBP1A (1.00) | FKBP1AABCC1FKBP4FKBP5 | |
| Biricodar SCHEMBL154547 | 0.76 | FKBP1A (1.00) | FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL7463764 | 0.75 | FKBP1A (0.61) | FKBP1AABCC1FKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | claimed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | claimed |