Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078853 | 0.79 | GAA (0.53) | MAPTGAAL3MBTL1GRM2 | |
| SCHEMBL11775136 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL7475826 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL13587825 | 0.73 | DHODH (0.37) | — | |
| SCHEMBL13774307 | 0.71 | DHPS (0.54) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL13587824 | 0.70 | MAPT (0.40) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL13266828 | 0.70 | KDM4E (0.52) | ALDH1A1KDM4EMAPTKMT2ANPC1 | |
| SCHEMBL14533084 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL13079283 | 0.69 | GRM2 (0.46) | GRM2 | |
| SCHEMBL12725423 | 0.69 | USP5 (0.47) | ALDH1A1KDM4EGAAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877185-A | THERAPY FOR CANCER OR RETROVIRUS | OCTAMER, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1996022791-A9 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | — | 1996-10-03 | — | — | WO | disclosed |
| WO-1996022791-A1 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | OCTAMER, INC. (US) | 1996-08-01 | — | — | WO | disclosed |