Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469838 | 1.00 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL9029523 | 0.84 | FFAR1 (0.45) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL9029531 | 0.84 | FFAR1 (0.45) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL28917337 | 0.83 | LMNA (0.40) | SMN1; SMN2LMNAKDM4ECYP1A2MAPT | |
| SCHEMBL28917335 | 0.83 | LMNA (0.40) | SMN1; SMN2LMNAKDM4ECYP1A2MAPT | |
| SCHEMBL16012976 | 0.79 | LMNA (0.55) | SMN1; SMN2LMNACYP1A2ALDH1A1MAPT | |
| SCHEMBL263217 | 0.76 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL5362724 | 0.76 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL5362727 | 0.76 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL1496589 | 0.76 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011112-A1 | TRICYCLIC INDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SYNTHELABO (FR) | 1998-03-19 | — | — | WO | disclosed |