SCHEMBL7469871

C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]([C]=O)CS

nearest known ligand 0.49

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	14/20	0.49

▸	NPY1R	P25929	9/20	0.49

▸	NPY5R	Q15761	8/20	0.49

▸	NPY2R	P49146	5/20	0.49

▸	PTPN1	P18031	3/20	0.45

▸	BACE1	P56817	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7459011	0.94	BACE1 (0.47)	NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL7419273	0.93	NPY4R (0.48)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL7415877	0.90	F2 (0.47)	NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL30475876	0.88	NPY4R (0.59)	NPY4RNPY1RNPY5RNPY2RPTPN1
SCHEMBL9614657	0.87	NPY4R (0.49)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL9614666	0.87	NPY4R (0.49)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL30799806	0.86	BACE1 (0.54)	NPY4RNPY1RNPY5RNPY2RPTPN1
SCHEMBL30836857	0.85	BACE1 (0.55)	NPY4RNPY1RNPY5RNPY2RPTPN1
SCHEMBL30799916	0.85	NPY4R (0.51)	NPY4RNPY1RNPY5RNPY2RPTPN1
SCHEMBL30799751	0.85	BACE1 (0.53)	NPY4RNPY1RNPY5RNPY2RPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1990014362-A1	ATRIAL PEPTIDE DERIVATIVES	ABBOTT LABORATORIES (US)	1990-11-29	—	—	WO	disclosed