SCHEMBL7419273

CCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]([C]=O)CS

nearest known ligand 0.48

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	12/20	0.48

▸	NPY1R	P25929	7/20	0.48

▸	NPY2R	P49146	5/20	0.48

▸	NPY5R	Q15761	5/20	0.48

▸	MMP2	P08253	8/20	0.42

▸	MMP1	P03956	3/20	0.42

▸	MMP3	P08254	3/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7469871	0.93	NPY4R (0.49)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL7415877	0.91	F2 (0.47)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL7459011	0.88	BACE1 (0.47)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL9614666	0.88	NPY4R (0.49)	NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL9614657	0.88	NPY4R (0.49)	NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL29533534	0.82	NPY4R (0.54)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL31074734	0.82	NPY4R (0.54)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL31074830	0.82	NPY4R (0.54)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL29534175	0.82	NPY4R (0.54)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL29419547	0.81	NPY4R (0.53)	NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0431113-A4	ATRIAL PEPTIDE DERIVATIVES	—	1992-01-22	—	—	EP	disclosed
EP-0431113-A1	ATRIAL PEPTIDE DERIVATIVES	ABBOTT LABORATORIES (US)	1991-06-12	—	—	EP	disclosed
WO-1990014362-A1	ATRIAL PEPTIDE DERIVATIVES	ABBOTT LABORATORIES (US)	1990-11-29	—	—	WO	disclosed