Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29018765 | 0.83 | MAPT (0.39) | MAPTL3MBTL1MEN1KMT2AAPAF1 | |
| SCHEMBL4272019 | 0.78 | ALDH1A1 (0.47) | MAPK8MEN1KMT2AAPAF1SCN9A | |
| SCHEMBL9228553 | 0.77 | MAPK8 (0.46) | MAPK8MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9120208 | 0.77 | SCN9A (0.49) | MAPK8MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL26149616 | 0.77 | MAPK8 (0.46) | MAPK8MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL1456723 | 0.77 | SCN9A (0.67) | MAPK8MEN1KMT2AAPAF1SCN9A | |
| SCHEMBL667594 | 0.77 | MEN1 (0.64) | MAPK8MAPTMEN1KMT2AAPAF1 | |
| SCHEMBL3665766 | 0.77 | BLM (0.47) | MAPK8MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL5119715 | 0.76 | MEN1 (0.57) | MAPK8MAPTL3MBTL1MAPK14MEN1 | |
| SCHEMBL30411682 | 0.74 | L3MBTL1 (0.49) | MAPK8L3MBTL1MEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |