SCHEMBL4272019

SCHEMBL4272019

c1ccc(Oc2ccnc(Oc3ccccc3)n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
MAPK8 P45983 1/20 0.47
LOXL2 Q9Y4K0 2/20 0.46
F10 P00742 1/20 0.46
LOX P28300 1/20 0.45
HAO1 Q9UJM8 1/20 0.44
MAP4K4 O95819 1/20 0.42
MEN1 O00255 1/20 0.42
APAF1 O14727 1/20 0.42
KMT2A Q03164 1/20 0.42
LTA4H P09960 1/20 0.42
TSHR P16473 1/20 0.42
SCN9A Q15858 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
PLK4 O00444 1/20 0.42
NPC1 O15118 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30411682 0.87 L3MBTL1 (0.49) ALDH1A1HTTMAPK8F10MEN1
SCHEMBL5251933 0.83 LOXL2 (0.46) ALDH1A1HTTLOXL2LOXTSHR
SCHEMBL17440402 0.81 ELANE (0.40) ALDH1A1HTTMAPK8LOXL2F10
SCHEMBL17440404 0.81 ELANE (0.40) ALDH1A1HTTMAPK8F10MEN1
SCHEMBL2904320 0.81 MEN1 (0.46) HTTF10MEN1APAF1KMT2A
SCHEMBL190518 0.80 PLAAT3 (0.48) ALDH1A1HTTLOXL2LOXHAO1
SCHEMBL7469887 0.78 HTT (0.46) ALDH1A1HTTLOXL2LOXHAO1
SCHEMBL12813082 0.78 POLB (0.54) ALDH1A1HTTLOXL2LOXMAP4K4
SCHEMBL7041105 0.78 HTT (0.50) ALDH1A1HTTMAPK8LOXL2LOX
SCHEMBL7041110 0.78 ALDH1A1 (0.46) ALDH1A1HTTLOXL2F10LOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6040813-A None JP disclosed
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed
JP-H0640813-A 2,6-SUBSTITUTED PYRIDINE HAVING HERBICIDAL EFFECT SHELL INTERNATL RES MAATSCHAPPIJ BV 1994-02-15 JP disclosed