Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695698 | 0.86 | MAPK1 (0.52) | MAPK1ALDH1A1CA12CA9TDP1 | |
| SCHEMBL4009107 | 0.86 | MAPK1 (0.52) | MAPK1ALDH1A1CA12CA9TDP1 | |
| SCHEMBL31415431 | 0.84 | ALDH1A1 (0.44) | MAPK1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL14269176 | 0.84 | ALDH1A1 (0.44) | MAPK1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL616678 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL3656114 | 0.83 | MAPK1 (0.57) | MAPK1ALDH1A1CA12CA9TDP1 | |
| Hydrochloric Acid SCHEMBL5875896 | 0.82 | ALDH1A1 (0.62) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL5875894 | 0.82 | ALDH1A1 (0.52) | MAPK1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL6156511 | 0.82 | KMT2A (0.65) | ALDH1A1TDP1CYP3A4ALOX15KMT2A | |
| SCHEMBL2721981 | 0.81 | ALDH1A1 (0.49) | MAPK1ALDH1A1TDP1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447490-A | Fluorescent probe with AIE (AIE) property, preparation method thereof and application of fluorescent probe in Al 3+ Application in recognition | 阜阳师范大学 | 2024-01-26 | — | — | CN | claimed |
| CN-117343068-A | Preparation method of FGFR2 inhibitor Lirafugatinib (RLY-4008) | 上海相辉医药科技有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-115557865-A | Thioether-promoted cysteine-based bioconjugation method | 南京工业大学 | 2023-01-03 | — | — | CN | claimed |
| CN-113880786-A | Synthesis method and antioxidant application of camphene aldehyde thiazole hydrazone derivative | 江西农业大学 | 2022-01-04 | — | — | CN | claimed |
| CN-110408026-B | Triarylamine polyimide containing pyrrole group and preparation method and application thereof | 中国人民解放军海军勤务学院 | 2021-09-03 | — | — | CN | claimed |
| CN-1765503-A | Quarternary ammonium salt of quinine compound, its preparation method and use | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2006-05-03 | — | — | CN | claimed |
| CN-117343068-B | Preparation method of FGFR2 inhibitor Lirafugratinib (RLY-4008) | 上海相辉医药科技有限公司 | 2026-04-28 | — | — | CN | disclosed |
| EP-4622716-A1 | SPIROCYCLIC DIHYDROPYRANOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| US-12404274-B2 | Macrocycles as factor xia inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-09-02 | — | — | US | disclosed |
| WO-2025110772-A1 | IMIDAZOLO-PYRIDINE DERIVATIVES AND USES THEREOF | 엘젠테라퓨틱스 주식회사 | 2025-05-30 | — | — | WO | disclosed |
| WO-2024112654-A1 | SPIROCYCLIC DIHYDROPYRANOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2024-05-30 | — | — | WO | disclosed |
| EP-3705480-B1 | CLASS OF AMINO-SUBSTITUTED NITROGEN-CONTAINING FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | SHANGHAI RINGENE BIOPHARMA CO LTD (CN) | 2024-02-28 | — | — | EP | disclosed |
| CN-117447490-A | Fluorescent probe with AIE (AIE) property, preparation method thereof and application of fluorescent probe in Al 3+ Application in recognition | 阜阳师范大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-1042421-C | Acridine derivatives | GLAXO LAB SA (FR) | 1999-03-10 | — | — | CN | disclosed |
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| CN-1186485-A | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 1998-07-01 | — | — | CN | disclosed |
| WO-1997049700-A1 | DERIVATIVES OF 2-(2-OXO-ETHYLIDENE)-IMIDAZOLIDIN-4-ONE AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | PFIZER INC. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |
| CN-1113241-A | Antifungal agent, and preparation method and intermediate thereof | EISAI CO LTD (JP) | 1995-12-13 | — | — | CN | disclosed |
| EP-0044704-A1 | Substituted pyrimidin-2-ones, the salts thereof, processes for their preparation, and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1982-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404274-B2 | Macrocycles as factor xia inhibitors | TFPI, TFPI2, F11 | MAPK1 650/4885ALDH1A1 4598/4885CA12 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.