Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PLD2 | O14939 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462229 | 0.95 | MCHR1 (0.62) | MCHR1SLC6A2SLC6A4KDM4EHSD17B10 | |
| SCHEMBL7460423 | 0.92 | MCHR1 (0.56) | MCHR1SLC6A2SLC6A4KDM4EHSD17B10 | |
| SCHEMBL7461371 | 0.92 | MCHR1 (0.56) | MCHR1SLC6A2SLC6A4KDM4EHSD17B10 | |
| SCHEMBL7465013 | 0.92 | MCHR1 (0.53) | MCHR1DRD3 | |
| SCHEMBL7459200 | 0.90 | MCHR1 (0.45) | MCHR1SLC6A2SLC6A4KDM4EHSD17B10 | |
| SCHEMBL7465486 | 0.89 | DRD4 (0.48) | MCHR1SLC6A2SLC6A4KDM4EHSD17B10 | |
| SCHEMBL7460142 | 0.87 | MCHR1 (0.56) | MCHR1SLC6A2SLC6A4DRD3 | |
| SCHEMBL7462536 | 0.86 | MCHR1 (0.58) | MCHR1SLC6A2SLC6A4DRD3 | |
| SCHEMBL7465415 | 0.85 | MCHR1 (0.56) | MCHR1SLC6A2SLC6A4DRD3DRD2 | |
| SCHEMBL7459832 | 0.85 | MCHR1 (0.51) | MCHR1SLC6A2SLC6A4KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |