Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.48 |
| ▸ | DRD3 | P35462 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463847 | 0.94 | DRD3 (0.48) | DRD4DRD3DRD2CACNA1GKCNH2 | |
| SCHEMBL7468710 | 0.93 | CACNA1G (0.43) | DRD4DRD3DRD2CACNA1GKCNH2 | |
| SCHEMBL7459200 | 0.90 | MCHR1 (0.45) | DRD4DRD3DRD2MCHR1SLC6A2 | |
| SCHEMBL7470101 | 0.89 | MCHR1 (0.56) | DRD4DRD3DRD2MCHR1SLC6A2 | |
| SCHEMBL7460484 | 0.87 | CACNA1G (0.43) | DRD4DRD3DRD2CACNA1GKCNH2 | |
| SCHEMBL7465649 | 0.86 | MCHR1 (0.46) | DRD4DRD3DRD2MCHR1SLC6A2 | |
| SCHEMBL7459832 | 0.84 | MCHR1 (0.51) | DRD4DRD3DRD2MCHR1SLC6A2 | |
| SCHEMBL7466835 | 0.83 | MCHR1 (0.45) | DRD4DRD3DRD2MCHR1SLC6A2 | |
| SCHEMBL7470930 | 0.83 | MCHR1 (0.42) | DRD3MCHR1 | |
| SCHEMBL7462229 | 0.83 | MCHR1 (0.62) | DRD4DRD3DRD2MCHR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |