SCHEMBL7465013

SCHEMBL7465013

Cc1ccc(C(CCCN2CCC(c3ccccc3)CC2)(CNC(=O)CNC(=O)c2cc3cc(Cl)ccc3[nH]2)c2ccc(C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.53
PYGL P06737 17/20 0.44
DRD3 P35462 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7460142 0.96 MCHR1 (0.56) MCHR1PYGLDRD3
SCHEMBL7462536 0.95 MCHR1 (0.58) MCHR1PYGLDRD3
SCHEMBL7461458 0.93 MCHR1 (0.53) MCHR1PYGLDRD3
SCHEMBL7470101 0.92 MCHR1 (0.56) MCHR1DRD3
SCHEMBL7465415 0.91 MCHR1 (0.56) MCHR1PYGLDRD3
SCHEMBL7460423 0.91 MCHR1 (0.56) MCHR1DRD3
SCHEMBL7470930 0.90 MCHR1 (0.42) MCHR1PYGLDRD3
SCHEMBL7467819 0.90 MCHR1 (0.53) MCHR1PYGLDRD3
SCHEMBL7463222 0.90 MCHR1 (0.53) MCHR1DRD3
SCHEMBL7468710 0.89 CACNA1G (0.43) MCHR1PYGLDRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1219294-A1 MELANIN CONCENTRATING HORMONE ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 2002-07-03 EP disclosed