Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469344 | 1.00 | GHSR (0.34) | GHSRYAP1TLR9TLR7BRD4 | |
| SCHEMBL7469349 | 1.00 | GHSR (0.34) | GHSRYAP1TLR9TLR7BRD4 | |
| SCHEMBL7470100 | 1.00 | GHSR (0.34) | GHSRYAP1TLR9TLR7BRD4 | |
| SCHEMBL6993841 | 0.84 | YAP1 (0.38) | GHSRYAP1TLR9TLR7NPC1 | |
| SCHEMBL6997323 | 0.80 | GHSR (0.38) | GHSRYAP1TLR9TLR7NPC1 | |
| SCHEMBL7473609 | 0.80 | GHSR (0.38) | GHSRYAP1TLR9TLR7NPC1 | |
| SCHEMBL9318090 | 0.77 | GHSR (0.37) | GHSRYAP1TLR9TLR7NPC1 | |
| SCHEMBL7466465 | 0.72 | TACR1 (0.32) | GHSRYAP1TLR9TLR7TACR1 | |
| SCHEMBL7463404 | 0.71 | YAP1 (0.33) | GHSRYAP1TLR9TLR7RORC | |
| SCHEMBL6995739 | 0.71 | SRD5A2 (0.40) | GHSRYAP1TLR9TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |