Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888308 | 0.82 | CES2 (0.47) | GAACES2CES1KCNN4CNR2 | |
| SCHEMBL8127998 | 0.82 | CES2 (0.47) | GAACES2CES1KCNN4CNR2 | |
| SCHEMBL3635938 | 0.82 | CES2 (0.47) | GAACES2CES1KCNN4CNR2 | |
| SCHEMBL4245530 | 0.81 | GAA (0.53) | GAACES2CES1KCNN4CNR2 | |
| SCHEMBL2662687 | 0.80 | CES2 (0.46) | GAACES2CES1CNR2IDO1 | |
| SCHEMBL11965195 | 0.80 | CES2 (0.46) | GAACES2CES1CNR2ALDH1A1 | |
| SCHEMBL6774538 | 0.78 | CES2 (0.61) | GAACES2CES1KCNN4CNR2 | |
| SCHEMBL27602661 | 0.78 | GAA (0.50) | GAACES2CES1KCNN4CNR2 | |
| SCHEMBL11214243 | 0.78 | GAA (0.50) | GAACES2CES1KCNN4CNR2 | |
| SCHEMBL7471753 | 0.77 | CES2 (0.49) | CES2CES1KCNN4IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103274961-A | Compositions and methods of treating cell proliferation disorders | KINEX PHARMACEUTICALS LLC | 2013-09-04 | — | — | CN | disclosed |
| CN-101184734-A | Compounds and methods for treating cell proliferation disorders | KINEX PHARMACEUTICALS LLC (US) | 2008-05-21 | — | — | CN | disclosed |
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| CN-1292697-A | Anti-viral compound | LILLY CO ELI (US) | 2001-04-25 | — | — | CN | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |