Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443157 | 1.00 | L3MBTL1 (0.50) | L3MBTL1SMPD2KDM4EGSK3BKMT2A | |
| N-Benzylmethylamine SCHEMBL9274090 | 0.84 | L3MBTL1 (0.44) | L3MBTL1SMPD2KDM4EGSK3BKMT2A | |
| SCHEMBL9003246 | 0.82 | SMPD2 (0.45) | L3MBTL1SMPD2KDM4EKMT2AALDH1A1 | |
| SCHEMBL7453130 | 0.80 | KMT2A (0.47) | L3MBTL1SMPD2KDM4EKMT2AALDH1A1 | |
| SCHEMBL7453131 | 0.80 | KMT2A (0.47) | L3MBTL1SMPD2KDM4EKMT2AALDH1A1 | |
| SCHEMBL6113113 | 0.79 | SMPD2 (0.47) | SMPD2 | |
| SCHEMBL6113112 | 0.79 | SMPD2 (0.47) | SMPD2 | |
| SCHEMBL6119288 | 0.79 | SMPD2 (0.47) | SMPD2 | |
| SCHEMBL7142898 | 0.79 | SMPD2 (0.43) | L3MBTL1SMPD2KDM4EKMT2AALDH1A1 | |
| SCHEMBL7448373 | 0.79 | SMPD2 (0.43) | L3MBTL1SMPD2KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950046-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2002-04-10 | — | — | EP | claimed |