Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 9/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470488 | 0.91 | HTR6 (0.44) | EGFRMETHTR6AURKA | |
| SCHEMBL7463091 | 0.90 | USP10 (0.50) | EGFRCNR1CNR2HTR6 | |
| SCHEMBL7468826 | 0.90 | EGFR (0.56) | EGFRHTR6 | |
| SCHEMBL7465224 | 0.89 | MAPT (0.44) | EGFRMETHTR6ABL1SRC | |
| SCHEMBL7463395 | 0.87 | HTT (0.55) | CLK4EGFRAURKARPS6KB1 | |
| SCHEMBL7473662 | 0.87 | USP10 (0.47) | EGFRCNR1CNR2HTR6 | |
| SCHEMBL7470206 | 0.87 | EGFR (0.52) | EGFRHTR6 | |
| SCHEMBL7475684 | 0.85 | EGFR (0.53) | EGFRMETHTR6 | |
| SCHEMBL7461647 | 0.85 | EGFR (0.48) | EGFRHTR6AURKARPS6KB1 | |
| SCHEMBL7465445 | 0.85 | HTR6 (0.55) | EGFRCNR1CNR2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |