Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | USP10 | Q14694 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | USP13 | Q92995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463091 | 0.91 | USP10 (0.50) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7465445 | 0.89 | HTR6 (0.55) | EGFRHTR6WDR5KMT2A | |
| SCHEMBL7470232 | 0.89 | CLK4 (0.46) | EGFRHTR6AURKARPS6KB1MET | |
| SCHEMBL7475684 | 0.88 | EGFR (0.53) | MAPTLMNAGAAALDH1A1EGFR | |
| SCHEMBL7473662 | 0.88 | USP10 (0.47) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7466331 | 0.87 | ALDH1A1 (0.48) | MAPTLMNAALDH1A1EGFRHTR6 | |
| SCHEMBL7458928 | 0.87 | EGFR (0.47) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7468826 | 0.87 | EGFR (0.56) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7525155 | 0.87 | EGFR (0.48) | MAPTLMNASMN1; SMN2EGFRHTR6 | |
| SCHEMBL7468699 | 0.86 | PDE5A (0.44) | MAPTLMNAGAAALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |