Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2872145 | 0.74 | MAPK1 (0.33) | NR1H2NR1H3 | |
| SCHEMBL2494815 | 0.74 | PREP (0.39) | NR1H2NR1H3PREPRORC | |
| SCHEMBL25870113 | 0.70 | PREP (0.38) | NR1H2PREP | |
| SCHEMBL24700390 | 0.68 | NR1H2 (0.35) | NR1H2NR1H3RORC | |
| SCHEMBL16040768 | 0.68 | NR1H2 (0.35) | NR1H2NR1H3RORC | |
| SCHEMBL2495889 | 0.66 | CYP3A4 (0.60) | NR1H2NR1H3PREP | |
| SCHEMBL28704785 | 0.66 | CYP3A4 (0.60) | NR1H2NR1H3PREP | |
| SCHEMBL3390628 | 0.66 | PREP (0.37) | NR1H2NR1H3PREP | |
| SCHEMBL31571841 | 0.65 | STS (0.31) | NR1H2NR1H3RORC | |
| SCHEMBL25295364 | 0.65 | NR1H2 (0.35) | NR1H2NR1H3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204659-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009122-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |