Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.82 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342601 | 0.90 | PTGS2 (1.00) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7462246 | 0.90 | PTGS2 (0.70) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL9088939 | 0.88 | PTGS2 (0.74) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8925428 | 0.88 | PTGS2 (0.65) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7461840 | 0.87 | PTGS2 (0.81) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL4587819 | 0.87 | PTGS2 (0.79) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8953880 | 0.85 | PTGS2 (0.81) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL16426376 | 0.85 | PTGS2 (0.76) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8925698 | 0.84 | PTGS2 (0.71) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7468667 | 0.84 | PTGS2 (0.71) | PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554829-B1 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |