Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504941 | 0.89 | PTGS2 (0.68) | PTGS2PTGS1CYP2C9ALOX5 | |
| SCHEMBL9088939 | 0.89 | PTGS2 (0.74) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7470436 | 0.88 | PTGS2 (0.82) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL9091142 | 0.84 | PTGS2 (0.69) | PTGS2PTGS1CYP2C9ALOX5 | |
| SCHEMBL7462246 | 0.83 | PTGS2 (0.70) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8925698 | 0.82 | PTGS2 (0.71) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7461840 | 0.81 | PTGS2 (0.81) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL5150500 | 0.80 | PTGS2 (0.60) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL3292551 | 0.80 | PTGS1 (0.66) | PTGS2PTGS1CYP2C9ALOX5 | |
| SCHEMBL8953888 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1CYP2C9ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |