Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HRAS | P01112 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7468841 | 0.99 | MEN1 (0.44) | MEN1KMT2ANAMPTALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7477192 | 0.89 | HRAS (0.42) | MEN1KMT2ANAMPTHRASESR1 | |
| SCHEMBL7472023 | 0.87 | HRAS (0.51) | MEN1KMT2AHRASESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7466261 | 0.85 | HRAS (0.49) | MEN1KMT2AALDH1A1HRASESR1 | |
| Hydrochloric Acid SCHEMBL7471999 | 0.84 | HRAS (0.52) | HRASESR1ESR2MAPT | |
| Hydrochloric Acid SCHEMBL7477283 | 0.82 | HRAS (0.50) | MEN1KMT2AHRASESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7475008 | 0.81 | HRAS (0.64) | HRASESR1ESR2MAPT | |
| SCHEMBL7469237 | 0.81 | HRAS (0.45) | MEN1KMT2AHRASESR1ESR2 | |
| SCHEMBL7467474 | 0.81 | HRAS (0.47) | HRASESR1ESR2MAPT | |
| SCHEMBL8298671 | 0.80 | HRAS (0.46) | MEN1KMT2AALDH1A1HRASESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |