Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478286 | 0.87 | ALDH1A1 (0.45) | ALDH1A1POLBPDE7AHTTTP53 | |
| SCHEMBL2088798 | 0.81 | ALDH1A1 (0.51) | ALDH1A1POLBHTTTP53MAPT | |
| SCHEMBL110420 | 0.79 | ALDH1A1 (0.52) | ALDH1A1POLBHTTTP53MAPT | |
| SCHEMBL7809597 | 0.79 | ALDH1A1 (0.52) | ALDH1A1POLBHTTTP53MAPT | |
| SCHEMBL1984158 | 0.78 | HSD17B10 (0.51) | ALDH1A1POLBPDE7AHTTTP53 | |
| SCHEMBL7472206 | 0.78 | ALDH1A1 (0.55) | ALDH1A1POLBPDE7AHTTTP53 | |
| SCHEMBL186720 | 0.77 | ALDH1A1 (0.55) | ALDH1A1POLBPDE7AHTTTP53 | |
| SCHEMBL1408560 | 0.77 | ALDH1A1 (0.48) | ALDH1A1POLBPDE7AHTTTP53 | |
| SCHEMBL5923594 | 0.77 | HTT (0.48) | ALDH1A1POLBPDE7AHTTTP53 | |
| SCHEMBL15688012 | 0.76 | ALDH1A1 (0.49) | ALDH1A1POLBPDE7AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |