Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470554 | 0.87 | ALDH1A1 (0.53) | ALDH1A1POLBPDE7AARMEN1 | |
| SCHEMBL7467657 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KMT2AHTTTP53LMNA | |
| SCHEMBL10453217 | 0.80 | ALDH3A1 (0.48) | ALDH1A1KMT2AMAPTHTTTP53 | |
| SCHEMBL7471531 | 0.80 | HSD17B10 (0.53) | ALDH1A1PDE7AKMT2AHTTTP53 | |
| SCHEMBL7476827 | 0.79 | ALDH1A1 (0.51) | ALDH1A1PDE7AMEN1KMT2AMAPT | |
| SCHEMBL186720 | 0.78 | ALDH1A1 (0.55) | ALDH1A1POLBPDE7AARMEN1 | |
| SCHEMBL1408560 | 0.78 | ALDH1A1 (0.48) | ALDH1A1POLBPDE7AMEN1KMT2A | |
| SCHEMBL3050424 | 0.77 | CNR2 (0.47) | ALDH1A1POLBARHTTTP53 | |
| SCHEMBL1408112 | 0.76 | ALDH1A1 (0.46) | ALDH1A1POLBPDE7AMEN1KMT2A | |
| SCHEMBL7470964 | 0.75 | HTT (0.53) | ALDH1A1KMT2AMAPTHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |