Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466158 | 0.95 | HTR6 (0.55) | HTR6PIK3CDPIK3R1EGFRMAPT | |
| SCHEMBL7467064 | 0.91 | HTR6 (0.52) | HTR6EGFRMAPTMAPK1CCNC | |
| SCHEMBL7471389 | 0.91 | MAPT (0.41) | HTR6PIK3CDPIK3R1EGFRMAPT | |
| SCHEMBL7468826 | 0.89 | EGFR (0.56) | HTR6EGFRMAPTMAPK1LMNA | |
| SCHEMBL7469830 | 0.88 | HTR6 (0.44) | HTR6EGFRMAPTMAPK1LMNA | |
| SCHEMBL7471400 | 0.88 | MAPT (0.42) | HTR6PIK3CDPIK3R1EGFRMAPT | |
| SCHEMBL7466302 | 0.86 | HTT (0.45) | HTR6EGFRMAPTMAPK1LMNA | |
| SCHEMBL7473892 | 0.86 | HTR6 (0.45) | HTR6MAPTMAPK1CCNCCDKN1A | |
| SCHEMBL7469494 | 0.86 | PDE5A (0.46) | MAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL7464149 | 0.86 | HTR6 (0.44) | HTR6MAPTMAPK1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |