Piperidine

Piperidine

SCHEMBL7470820

C1CCNCC1.CCC(=O)Nc1c(C)cc(C(=O)N2CCC(N(C)CCc3ccccc3)CC2)cc1C

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
ABL1 P00519 6/20 0.41
RIN1 Q13671 6/20 0.41
OPRM1 P35372 2/20 0.37
CHIA Q9BZP6 1/20 0.37
MEN1 O00255 1/20 0.36
NPBWR1 P48145 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MCHR1 Q99705 1/20 0.36
DRD4 P21917 1/20 0.35
CCR5 P51681 2/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2831451 0.93 L3MBTL1 (0.44) L3MBTL1ABL1RIN1OPRM1CHIA
Hydrochloric Acid SCHEMBL7469382 0.92 L3MBTL1 (0.44) L3MBTL1ABL1RIN1OPRM1CHIA
Hydrochloric Acid SCHEMBL4020264 0.91 L3MBTL1 (0.43) L3MBTL1ABL1RIN1OPRM1CHIA
Hydrochloric Acid SCHEMBL7470582 0.86 L3MBTL1 (0.41) L3MBTL1ABL1RIN1OPRM1CHIA
Oxalic Acid SCHEMBL7475838 0.85 L3MBTL1 (0.42) L3MBTL1ABL1RIN1OPRM1MEN1
Hydrochloric Acid SCHEMBL7475741 0.84 L3MBTL1 (0.40) L3MBTL1ABL1RIN1OPRM1CHIA
SCHEMBL7475845 0.84 L3MBTL1 (0.42) L3MBTL1ABL1RIN1OPRM1MEN1
SCHEMBL7466257 0.83 ABL1 (0.44) L3MBTL1ABL1RIN1OPRM1MEN1
Hydrochloric Acid SCHEMBL7464869 0.82 L3MBTL1 (0.42) L3MBTL1ABL1RIN1CHIAMEN1
SCHEMBL27675909 0.81 L3MBTL1 (0.44) L3MBTL1ABL1RIN1OPRM1CHIA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0650476-B1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMA CO LTD (JP) 2002-06-26 EP claimed