Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831451 | 0.90 | L3MBTL1 (0.44) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7469382 | 0.89 | L3MBTL1 (0.44) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL7475838 | 0.89 | L3MBTL1 (0.42) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4020264 | 0.88 | L3MBTL1 (0.43) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7470582 | 0.85 | L3MBTL1 (0.41) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| Piperidine SCHEMBL7470820 | 0.84 | L3MBTL1 (0.42) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| SCHEMBL7466257 | 0.83 | ABL1 (0.44) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7475741 | 0.83 | L3MBTL1 (0.40) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| SCHEMBL27675909 | 0.79 | L3MBTL1 (0.44) | L3MBTL1ABL1RIN1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7470813 | 0.79 | L3MBTL1 (0.42) | L3MBTL1ABL1RIN1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |