Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557746 | 0.83 | TSHR (0.45) | PPARGTSHRXIAPGSK3BADK | |
| SCHEMBL8553542 | 0.82 | TSHR (0.49) | PPARGTSHRXIAPALDH1A1SMN1; SMN2 | |
| SCHEMBL8553538 | 0.82 | TSHR (0.49) | PPARGTSHR | |
| SCHEMBL8554854 | 0.82 | TSHR (0.46) | PPARGTSHRXIAPGSK3BADK | |
| SCHEMBL8605562 | 0.81 | TSHR (0.50) | PPARGTSHRXIAPALDH1A1SMN1; SMN2 | |
| SCHEMBL8554111 | 0.81 | TSHR (0.48) | PPARGTSHRXIAPALDH1A1SMN1; SMN2 | |
| SCHEMBL8557074 | 0.80 | TSHR (0.47) | PPARGTSHRXIAPALDH1A1SMN1; SMN2 | |
| SCHEMBL7468643 | 0.80 | TSHR (0.42) | PPARGTSHRXIAPGSK3BADK | |
| SCHEMBL8554156 | 0.79 | TSHR (0.38) | PPARGTSHRXIAPGSK3BADK | |
| SCHEMBL8602742 | 0.79 | TSHR (0.55) | PPARGTSHRXIAPGSK3BADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | claimed |