Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214819 | 0.80 | HDAC4 (0.41) | USP2ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL1553978 | 0.79 | TAAR1 (0.52) | PBRM1KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL2760210 | 0.79 | TAAR1 (0.52) | PBRM1KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL3602217 | 0.78 | AOC3 (0.34) | TAAR1 | |
| SCHEMBL7498722 | 0.78 | TRPA1 (0.41) | KDM4EMEN1ALDH1A1KMT2ATAAR1 | |
| SCHEMBL3603421 | 0.78 | AOC3 (0.34) | TAAR1 | |
| SCHEMBL7821122 | 0.78 | TAAR1 (0.33) | TAAR1 | |
| SCHEMBL3617032 | 0.78 | AOC3 (0.34) | TAAR1 | |
| SCHEMBL2179249 | 0.77 | RIPK1 (0.36) | TAAR1TRPA1 | |
| SCHEMBL2005856 | 0.76 | TRPA1 (0.39) | KDM4EALDH1A1MAPTHSD17B10TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997042168-A1 | THIO DERIVATIVES OF HYDROXAMIC ACIDS | ZENECA LIMITED (GB) | 1997-11-13 | — | — | WO | disclosed |