Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461166 | 0.82 | IDO1 (0.41) | IDO1MAOBFFAR4FFAR1KDM4E | |
| SCHEMBL7466725 | 0.78 | RXRA (0.44) | IDO1MAOBMAOATACR1FFAR4 | |
| SCHEMBL7463218 | 0.77 | ABCB1 (0.47) | IDO1KDM4EALDH1A1 | |
| SCHEMBL7458394 | 0.77 | PARP10 (0.43) | FFAR1ALDH1A1 | |
| SCHEMBL7466776 | 0.76 | GSTP1 (0.42) | MAOBMAOAALOX5KDM4E | |
| SCHEMBL7466685 | 0.75 | MAOB (0.47) | IDO1MAOBTACR1FFAR4FFAR1 | |
| SCHEMBL7821243 | 0.75 | DRD1 (0.38) | ALDH1A1 | |
| SCHEMBL3324331 | 0.74 | RXRA (0.44) | IDO1MAOBMAOAARKDM4E | |
| SCHEMBL7024874 | 0.74 | IDO1 (0.53) | IDO1MAOBMAOATACR1FFAR4 | |
| SCHEMBL7455789 | 0.73 | RXRA (0.43) | MAOBFFAR4FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |