Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466685 | 0.86 | MAOB (0.47) | RXRARXRBRXRGFFAR1FFAR4 | |
| SCHEMBL7466776 | 0.85 | GSTP1 (0.42) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL7455789 | 0.85 | RXRA (0.43) | RXRARXRBRXRGFFAR1FFAR4 | |
| SCHEMBL7460079 | 0.82 | RXRA (0.40) | RXRARXRBRXRGFFAR1FFAR4 | |
| SCHEMBL7468369 | 0.82 | IKBKB (0.48) | RXRARXRBRXRGCYP19A1CYP11B1 | |
| SCHEMBL697658 | 0.80 | MAOB (0.46) | PTPN1MAOBIDO1MAOA | |
| SCHEMBL7461463 | 0.80 | ABCB1 (0.44) | FFAR1FFAR4MAOB | |
| SCHEMBL6754376 | 0.79 | MAOB (0.51) | MAOBIDO1MAOA | |
| SCHEMBL7470952 | 0.78 | IDO1 (0.45) | FFAR1FFAR4TACR1MAOBIDO1 | |
| SCHEMBL7466994 | 0.78 | MAOB (0.51) | RXRARXRBRXRGFFAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |