Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458897 | 0.83 | ABL1 (0.55) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL4903199 | 0.79 | IKBKB (0.64) | RAB9ANPC1MAPTCASP3SENP8 | |
| SCHEMBL14088822 | 0.78 | IKBKB (0.57) | RAB9ANPC1MAPTCASP3SENP8 | |
| SCHEMBL2533488 | 0.76 | TSHR (0.84) | RAB9ANPC1MAPTCASP3SENP8 | |
| SCHEMBL4898704 | 0.75 | ADH5 (0.72) | RAB9ANPC1MAPTALDH1A1CASP3 | |
| SCHEMBL4902208 | 0.74 | ABL1 (0.67) | RAB9ANPC1MEN1KMT2APRKACA | |
| SCHEMBL2532397 | 0.74 | LMNA (0.78) | MAPTLMNAMEN1ALOX15TSHR | |
| SCHEMBL7560816 | 0.74 | CYP1A2 (0.53) | MAPTKDM4EALDH1A1LMNAALOX15 | |
| SCHEMBL7462511 | 0.73 | IKBKB (0.64) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL4902560 | 0.73 | ABL1 (0.72) | RAB9ANPC1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |