Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475678 | 0.97 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL7484961 | 0.97 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL7534448 | 0.89 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL7480841 | 0.89 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL7474224 | 0.88 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL7477298 | 0.88 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL7468853 | 0.88 | ALOX5 (0.60) | ALOX5 | |
| SCHEMBL7477587 | 0.87 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL7477954 | 0.87 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9395089 | 0.86 | ALOX5 (0.56) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | claimed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | claimed |
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | disclosed |