Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27454258 | 0.86 | TAAR1 (0.44) | TAAR1IDO1AGXT | |
| SCHEMBL7470784 | 0.81 | CHRM2 (0.42) | TAAR1 | |
| SCHEMBL7464364 | 0.80 | HTR2A (0.45) | TAAR1IDO1 | |
| SCHEMBL10494813 | 0.79 | KCNH2 (0.49) | CNR2 | |
| SCHEMBL6559348 | 0.79 | KCNH2 (0.49) | CNR2 | |
| SCHEMBL6380984 | 0.79 | KCNH2 (0.49) | CNR2 | |
| SCHEMBL10494779 | 0.79 | KCNH2 (0.49) | CNR2 | |
| SCHEMBL2549406 | 0.79 | KCNH2 (0.49) | CNR2 | |
| SCHEMBL9386106 | 0.79 | KCNH2 (0.49) | CNR2 | |
| SCHEMBL442769 | 0.79 | KCNH2 (0.49) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |