Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471041 | 0.93 | KMT2A (0.52) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL7470594 | 0.84 | USP2 (0.53) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL7463472 | 0.83 | HSD17B10 (0.48) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL8601457 | 0.83 | USP2 (0.39) | KMT2AMEN1GAAMAPK1USP2 | |
| SCHEMBL7475258 | 0.82 | HSD17B10 (0.44) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL7464320 | 0.82 | USP2 (0.38) | KMT2AMEN1GAAMAPTMAPK1 | |
| SCHEMBL7473281 | 0.81 | MEN1 (0.38) | KMT2AMEN1GAAMAPK1USP2 | |
| SCHEMBL7472425 | 0.81 | PARP1 (0.45) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL7476310 | 0.79 | USP2 (0.45) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL7468831 | 0.78 | USP2 (0.42) | KMT2AMEN1GAAUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |