Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042749 | 0.88 | TSHR (0.68) | TSHRKMT2AGAAMEN1CHRNA7 | |
| SCHEMBL4812999 | 0.84 | TSHR (0.67) | TSHRKMT2AGAAMEN1CHRNA7 | |
| SCHEMBL9040899 | 0.83 | TSHR (0.71) | TSHRKMT2AGAAMEN1CHRNA7 | |
| SCHEMBL9042515 | 0.79 | TSHR (0.65) | TSHRKMT2AGAAMEN1CHRNA7 | |
| SCHEMBL11580874 | 0.79 | CHRNA7 (0.45) | TSHRKMT2AGAAMEN1CHRNA7 | |
| SCHEMBL6305731 | 0.78 | TSHR (0.61) | TSHRKMT2AGAAMEN1CHRNA7 | |
| SCHEMBL9590842 | 0.78 | TSHR (0.56) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL7533362 | 0.78 | TSHR (0.75) | TSHRKMT2AGAAMEN1CHRNA7 | |
| SCHEMBL1138721 | 0.78 | KMT2A (0.84) | TSHRKMT2AGAAMEN1CHRNA7 | |
| SCHEMBL7478396 | 0.77 | NAAA (0.44) | TSHRKMT2AGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389421-B1 | Poly(1-hydrocarbyloxy-2,2,6,6-tetraalkylpiperidine) light stabilizers | CIBA GEIGY AG (CH) | 1994-04-27 | — | — | EP | claimed |
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| US-5574162-A | CONTAIN REACTIVE FUNCTIONAL GROUP, I.E., HYDROXY, AMINO, ISOCYANATO, GLYCIDYLOXY, TRIHYDROXYSILYL OR TRIALKOXYSILYL, WHICH CAN BE CHEMICALLY ATTACHED TO POLYMER SUBSTRATES | CIBA-GEIGY CORPORATION (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0389419-B1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA GEIGY AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| US-5442071-A | Photostability | CIBA-GEIGY CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-5359069-A | Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers | CIBA-GEIGY CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0389421-B1 | Poly(1-hydrocarbyloxy-2,2,6,6-tetraalkylpiperidine) light stabilizers | CIBA GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |
| US-5286865-A | Contain reactive functional group which can be chemically attached to selected polymer substrates | CIBA-GEIGY CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| US-5189086-A | Polysubstituted N-hydrocarbyloxy hindered amine light stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| US-5145893-A | Photostability | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-5021577-A | For polymers | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0389421-A1 | Poly(1-hydrocarbyloxy-2,2,6,6-tetraalkylpiperidine) light stabilizers | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389419-A1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0309402-A1 | N-substituted hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |