Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474113 | 0.90 | EGFR (0.55) | EGFRMAPTABCG2PGK1PDGFRB | |
| SCHEMBL7475194 | 0.81 | EGFR (0.66) | EGFRHTT | |
| SCHEMBL7473900 | 0.81 | EGFR (0.56) | EGFRMAPTABCG2PDGFRB | |
| SCHEMBL7457697 | 0.81 | EGFR (0.62) | EGFRMAPTMEN1KMT2APDGFRB | |
| SCHEMBL7468297 | 0.80 | SMN1; SMN2 (0.44) | EGFRMAPTKMT2AABCG2 | |
| SCHEMBL7474181 | 0.80 | MAPK1 (0.56) | EGFRMAPTHTT | |
| SCHEMBL7474842 | 0.78 | RXFP1 (0.62) | EGFRHTTABCG2PGK1 | |
| SCHEMBL7471567 | 0.78 | PIK3CD (0.62) | EGFRMAPTHTT | |
| SCHEMBL7529433 | 0.78 | EGFR (0.51) | EGFRMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL7470644 | 0.77 | EGFR (0.53) | EGFRABCG2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |