Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.53 |
| ▸ | CCNC | P24863 | 1/20 | 0.52 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471567 | 0.94 | PIK3CD (0.62) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7469664 | 0.91 | HTT (0.63) | MAPK1EGFRHTTMAPTCNR1 | |
| SCHEMBL7462734 | 0.90 | EGFR (0.55) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7528662 | 0.90 | EGFR (0.52) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7469795 | 0.90 | EGFR (0.60) | MAPK1EGFRHTTLMNAAPP | |
| SCHEMBL7474665 | 0.89 | HTT (0.62) | MAPK1EGFRHTTMAPTRAB9A | |
| SCHEMBL7475626 | 0.89 | HTT (0.52) | MAPK1EGFRHTTNR2F2SMN1; SMN2 | |
| SCHEMBL7464363 | 0.89 | HTT (0.54) | MAPK1EGFRHTTCNR1CNR2 | |
| SCHEMBL7475194 | 0.89 | EGFR (0.66) | MAPK1EGFRHTTLMNARAB9A | |
| SCHEMBL7470831 | 0.89 | EGFR (0.53) | MAPK1EGFRHTTMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |