Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474181 | 0.88 | MAPK1 (0.56) | EGFRMAPTSMN1; SMN2 | |
| SCHEMBL7471567 | 0.86 | PIK3CD (0.62) | EGFRMAPT | |
| SCHEMBL7475194 | 0.85 | EGFR (0.66) | EGFRSMN1; SMN2 | |
| SCHEMBL7469700 | 0.84 | EGFR (0.54) | EGFRMAPT | |
| SCHEMBL7474806 | 0.84 | EGFR (0.52) | EGFRPDGFRBMAPT | |
| SCHEMBL7474113 | 0.83 | EGFR (0.55) | EGFRPDGFRBFBP1MAPT | |
| SCHEMBL7461530 | 0.83 | PKM (0.56) | EGFRMAPTSMN1; SMN2 | |
| SCHEMBL7463424 | 0.82 | EGFR (0.50) | EGFRPDGFRBMEN1MAPTKMT2A | |
| SCHEMBL7464363 | 0.81 | HTT (0.54) | EGFRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7465660 | 0.81 | EGFR (0.56) | EGFRMEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |