⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623764 | 0.63 | SLC6A2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL8461636 | 0.61 | — | — | |
| SCHEMBL5833030 | 0.61 | — | — | |
| SCHEMBL2649526 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL9410202 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL9410186 | 0.60 | — | — | |
| SCHEMBL664080 | 0.58 | — | — | |
| SCHEMBL16919350 | 0.58 | ALDH1A1 (0.33) | — | |
| SCHEMBL2006920 | 0.57 | — | — | |
| SCHEMBL1814521 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937708-B1 | Sulphonamide derivatives | LILLY CO ELI (US) | 2002-12-18 | — | — | EP | claimed |
| US-6362230-B1 | ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY | 2002-03-26 | — | — | US | claimed |
| US-6174922-B1 | FOR POTENTIATING GLUTAMATE RECEPTOR FUNCTION IN WARM BLOODED MAMMAL | ELI LILLY AND COMPANY | 2001-01-16 | — | — | US | claimed |
| EP-0937708-A2 | sulphonamide derivatives | ELI LILLY AND COMPANY (US) | 1999-08-25 | — | — | EP | claimed |
| EP-0937708-B1 | Sulphonamide derivatives | LILLY CO ELI (US) | 2002-12-18 | — | — | EP | disclosed |
| US-6362230-B1 | ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6174922-B1 | FOR POTENTIATING GLUTAMATE RECEPTOR FUNCTION IN WARM BLOODED MAMMAL | ELI LILLY AND COMPANY | 2001-01-16 | — | — | US | disclosed |
| EP-0937708-A2 | sulphonamide derivatives | ELI LILLY AND COMPANY (US) | 1999-08-25 | — | — | EP | disclosed |