Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192389 | 0.83 | HPGD (0.54) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10998190 | 0.81 | HPGD (0.53) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11722373 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL4239545 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL4086194 | 0.81 | F2 (0.52) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL11791471 | 0.79 | HPGD (0.51) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11624199 | 0.78 | HPGD (0.35) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9699843 | 0.77 | GSK3B (0.46) | ALDH1A1RAB9AKMT2AGSK3BDAO | |
| SCHEMBL13960318 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL28736805 | 0.76 | KMT2A (0.46) | ALDH1A1HTTRAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920319-A4 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001070227-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| US-6150522-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0920319-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997044041-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-11-27 | — | — | WO | disclosed |
| US-4499286-A | Derivatives of thienylacetic acid amides and their pharmaceutically acceptable acid salts and a process for the preparation thereof | Leavoson-Gesellschaft m.b.H. & Co. KG (AT) | 1985-02-12 | — | — | US | disclosed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |