Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472736 | 0.81 | ALDH1A1 (0.47) | F2ALDH1A1KMT2ASMN1; SMN2HTT | |
| SCHEMBL192389 | 0.81 | HPGD (0.54) | F2ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4239545 | 0.79 | ALDH1A1 (0.50) | F2ALDH1A1KMT2ASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL10998190 | 0.79 | HPGD (0.53) | F2ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11722373 | 0.79 | ALDH1A1 (0.46) | F2ALDH1A1KMT2ASMN1; SMN2HTT | |
| Methyl Alcohol SCHEMBL11791471 | 0.78 | HPGD (0.51) | F2ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL19580455 | 0.77 | MEN1 (0.44) | ALDH1A1KMT2ASMN1; SMN2MEN1ACACA | |
| SCHEMBL11104922 | 0.75 | HDAC1 (0.44) | ALDH1A1KMT2ASMN1; SMN2MEN1GSK3B | |
| SCHEMBL29418642 | 0.75 | KMT2A (0.43) | F2ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4096475 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105942-B | Compounds useful as potassium channel openers | 阿库西亚医疗有限责任公司 | 2024-07-12 | — | — | CN | disclosed |
| US-11884642-B2 | Compounds useful as potassium channel openers | ACOUSIA THERAPEUTICS GMBH (DE) | 2024-01-30 | — | — | US | disclosed |
| US-11737463-B2 | Pyridine and pyrazine compounds | BASF SE (DE) | 2023-08-29 | — | — | US | disclosed |
| CN-110312710-B | Compounds useful as potassium channel openers | 阿库西亚医疗有限责任公司 | 2022-02-15 | — | — | CN | disclosed |
| US-20210145002-A1 | PYRIDINE AND PYRAZINE COMPOUNDS | BASF SE (DE) | 2021-05-20 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| EP-1861384-A1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Sterix Limited (GB) | 2007-12-05 | — | — | EP | disclosed |
| CN-101031566-A | Proline derivatives | MERCK PATENT GMBH (DE) | 2007-09-05 | — | — | CN | disclosed |
| WO-2006100502-A1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | STERIX LIMITED (GB) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884642-B2 | Compounds useful as potassium channel openers | KCNA7, KCNA4, KCNA1 | F2 3745/4885ALDH1A1 2790/4885KMT2A 1378/4885 |
| US-11737463-B2 | Pyridine and pyrazine compounds | NDUFS5, IL5, NDUFS4 | F2 149/4885ALDH1A1 231/4885KMT2A 2890/4885 |
| US-20210145002-A1 | PYRIDINE AND PYRAZINE COMPOUNDS | NDUFS5, IL5, NDUFS4 | F2 149/4885ALDH1A1 231/4885KMT2A 2890/4885 |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | F2 2365/4885ALDH1A1 437/4885KMT2A 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.