SCHEMBL74729

SCHEMBL74729

COCc1c(F)c(F)c(COC(=O)C2C(C=C(C)C#N)C2(C)C)c(F)c1F

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
LMNA P02545 3/20 0.42
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
ADRA2A P08913 1/20 0.35
CNR1 P21554 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12078854 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL359326 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL74728 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL1812630 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL14502943 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL1815554 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL12078772 1.00 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL29843251 0.95 TDP1 (0.49) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL29843327 0.95 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL29911420 0.94 TDP1 (0.51) TDP1MEN1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
EP-4640053-A2 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC Corporation (US) 2025-10-29 EP claimed
WO-2025006595-A1 BAIT COMPOSITIONS FMC CORPORATION (US) 2025-01-02 WO claimed
US-20240057602-A1 DIAMIDE INSECTICIDE COMPOSITIONS FMC IP TECHNOLOGY GMBH (CH) 2024-02-22 US claimed
WO-2023203038-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-10-26 WO claimed
CN-116784339-A Pesticide composition and application thereof 山东省联合农药工业有限公司 2023-09-22 CN claimed
US-20230026036-A1 DIAMIDE SUSPENSION CONCENTRATE COMPOSITIONS FMC IP TECHNOLOGY GMBH (CH) 2023-01-26 US claimed
EP-3887354-B1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2023-01-04 EP claimed
US-20220394974-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC CORPORATION 2022-12-15 US claimed
EP-4075972-A1 DIAMIDE SUSPENSION CONCENTRATE COMPOSITIONS FMC CORPORATION (US) 2022-10-26 EP claimed
EP-2136643-A2 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING HARMFUL INSECTS Sumitomo Chemical Company, Limited (JP) 2009-12-30 EP claimed
EP-2136644-A2 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING HARMFUL INSECTS Sumitomo Chemical Company, Limited (JP) 2009-12-30 EP claimed
US-20090081132-A1 Water-borne aerosol composition SUMITOMO CHEMICAL COMPANY, LIMITED 2009-03-26 US claimed
WO-2009031692-A2 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 WO claimed
WO-2009031697-A2 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 WO claimed
WO-2008123571-A2 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING HARMFUL INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-16 WO claimed
WO-2008123564-A2 PESTICIDAL AEROSOL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-16 WO claimed
WO-2008123573-A2 PESTICIDAL AEROSOL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-16 WO claimed
WO-2008123574-A2 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING HARMFUL INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-16 WO claimed
WO-2008108235-A2 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING A PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240057602-A1 DIAMIDE INSECTICIDE COMPOSITIONS DDT, PLCG2, PLD2 TDP1 539/4885MEN1 3579/4885KMT2A 2162/4885
US-20220394974-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES ACHE, DDT, BCHE TDP1 1558/4885MEN1 2727/4885KMT2A 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.