Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 9/20 | 0.49 |
| ▸ | THRA | P10827 | 5/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829095 | 0.92 | MEN1 (0.58) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL7989856 | 0.90 | THRB (0.46) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL5566665 | 0.85 | MEN1 (0.58) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL8347711 | 0.85 | THRB (0.52) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL7999085 | 0.84 | THRB (0.53) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL7998709 | 0.83 | THRB (0.43) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL8005262 | 0.83 | THRB (0.43) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL7477395 | 0.83 | THRB (0.53) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL24781304 | 0.83 | THRB (0.55) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL6479192 | 0.82 | KMT2A (0.50) | MEN1NR1I2KMT2AP2RX7ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831088-B1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2002-11-27 | — | — | EP | claimed |
| EP-0831088-B1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5985875-A | USEFUL AS ANTI-PROTOZOAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0831088-A1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-25 | — | — | EP | disclosed |