Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.46 |
| ▸ | THRA | P10827 | 4/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005262 | 0.93 | THRB (0.43) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7998709 | 0.93 | THRB (0.43) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7472949 | 0.90 | MEN1 (0.51) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL8002833 | 0.83 | P2RX7 (0.39) | THRBTHRAP2RX7MEN1KMT2A | |
| SCHEMBL7989781 | 0.83 | THRB (0.48) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7829095 | 0.81 | MEN1 (0.58) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL8347711 | 0.81 | THRB (0.52) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7999085 | 0.81 | THRB (0.53) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7477395 | 0.80 | THRB (0.53) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL24781304 | 0.79 | THRB (0.55) | THRBTHRAP2RX7MEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | claimed |
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |